2017年3月26日 星期日

People who wake at night with an urge to go to the loo may need to cut back on salt in their diets

People who wake at night with an urge to go to the loo may need to cut back on salt in their diets, doctors from Japan are suggesting.

Night-time loo trips 'linked to salt in diet' http://bbc.in/2n48vd4

2017年3月25日 星期六

「The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors」


[驚世駭俗的肺文]
從國中學到現在的肺⋯⋯難道不是肺??😰😰
這個結論可是自然界大事啊!!
沒看過原文不表示意見,坐等專家打臉or驗證
http://www.yigoonet.com/article/22536254.html Nature驚人發現:肺竟然是造血器官 近日,來自加州大學舊金山分校的一個科學家小組在Nature雜誌上發表了一篇題為 「The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors」的新成果,他們首次證實肺是個造血器官,
PTT.CC

The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

Nature
 
 
doi:10.1038/nature21706
Received
 
Accepted
 
Published online
 
Platelets are critical for haemostasis, thrombosis, and inflammatory responses12, but the events that lead to mature platelet production remain incompletely understood3. The bone marrow has been proposed to be a major site of platelet production, although there is indirect evidence that the lungs might also contribute to platelet biogenesis4567. Here, by directly imaging the lung microcirculation in mice8, we show that a large number of megakaryocytes circulate through the lungs, where they dynamically release platelets. Megakaryocytes that release platelets in the lungs originate from extrapulmonary sites such as the bone marrow; we observed large megakaryocytes migrating out of the bone marrow space. The contribution of the lungs to platelet biogenesis is substantial, accounting for approximately 50% of total platelet production or 10 million platelets per hour. Furthermore, we identified populations of mature and immature megakaryocytes along with haematopoietic progenitors in the extravascular spaces of the lungs. Under conditions of thrombocytopenia and relative stem cell deficiency in the bone marrow9, these progenitors can migrate out of the lungs, repopulate the bone marrow, completely reconstitute blood platelet counts, and contribute to multiple haematopoietic lineages. These results identify the lungs as a primary site of terminal platelet production and an organ with considerable haematopoietic potential.

At a glance

陳耀昌 http://www.nature.com/....../ncurrent/full/nature21706.html
The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors : Nature : Nature Research
NATURE.COM


google traslate

肺是血小板生物發生的一個部位和造血祖細胞

性質
 
 
doi:10.1038 / nature21706
收到
 
公認
 
在線發布
 
血小板是止血,血栓形成,和炎症反應的關鍵12,但是這導致成熟血小板生成的事件仍然不完全理解3骨髓已經提出是血小板產生的主要部位,雖然有間接的證據表明,肺也可能有助於血小板的生物合成4567在這裡,通過直接成像小鼠的肺微循環8,我們顯示大量巨核細胞通過肺循環,在那裡它們動態釋放血小板。在肺中釋放血小板的巨核細胞源自肺外部位如骨髓; 我們觀察到巨大的巨核細胞遷移出骨髓空間。肺對血小板生物發生的貢獻是巨大的,佔血小板總產量的約50%或每小時1000萬片血小板。此外,我們確定了成熟和未成熟的巨核細胞與造血祖細胞在肺外血管空間中的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。肺對血小板生物發生的貢獻是巨大的,佔血小板總產量的約50%或每小時1000萬片血小板。此外,我們確定了成熟和未成熟的巨核細胞與造血祖細胞在肺外血管空間中的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。肺對血小板生物發生的貢獻是巨大的,佔血小板總產量的約50%或每小時1000萬片血小板。此外,我們確定了成熟和未成熟的巨核細胞與造血祖細胞在肺外血管空間中的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。佔血小板總產量的約50%或每小時1000萬片血小板。此外,我們確定了成熟和未成熟的巨核細胞與造血祖細胞在肺外血管空間中的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。佔血小板總產量的約50%或每小時1000萬片血小板。此外,我們確定了成熟和未成熟的巨核細胞與造血祖細胞在肺外血管空間中的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。我們在肺外血管空間中鑑定了成熟和未成熟的巨核細胞與造血祖細胞的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。我們在肺外血管空間中鑑定了成熟和未成熟的巨核細胞與造血祖細胞的種群。下在骨髓中血小板和相對幹細胞缺乏條件9,這些祖細胞可以遷移出肺,重新填充的骨髓,完全重建血液血小板計數,並且向多個造血譜系。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。並為多種造血譜係作出貢獻。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。並為多種造血譜係作出貢獻。這些結果將肺部識別為終末血小板生成的主要部位和具有相當大的造血潛能的器官。

味道的心理學 (Charles Spence, Oxford),


......味道透過鼻子傳到腦去"分析",所以現行的超商等咖非杯設計"不佳"......有興趣的讀者可進一步到YouTube,以Charles Spence Oxford,搜索,至少還有近十片的"研究-試驗"可看!
-5:31
12,144 次觀看
BBC Breakfast 新增了一段影片
21 小時
How does the type, colour or shape of your plate or bowl effect how your food taste? Does background music make food taste sweeter?
Professor Charles Spence, a food psychologist from the University of Oxford, explains with the help of a few jellybeans...




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