01 | The Atomic Revolution - ABC Michelle Simmons AO 教授

澳洲駐台辦事處 Australian Office in Taipei
·





澳洲廣播公司（Australian Broadcasting Corporation, ABC）的「鮑伊爾講座 Boyer Lectures」這次邀請到傑出量子物理學家，同時也是2023年「澳洲總理科學獎」桂冠得主 Michelle Simmons AO 教授，進行一連串共4場的專題講座。日前，首場「原子革命」已上線，下一場預計於明（26）日播出。
澳洲是量子運算研發的先驅，而Simmons教授更是此新興領域的翹楚與領頭羊，屢屢取得重要突破。有興趣的人可千萬不要錯過線上收看和收聽的機會。
#量子物理 #量子運算 #科技
#女科技人 #科技女孩
#知識星期三 ​
It was fantastic to hear Australian quantum physicist Professor Michelle Simmons AO deliver the first 2023 Boyer Lecture on ‘the Atomic Revolution’. Australia is a pioneer in quantum computing and Professor Simmons is at the forefront of this fast-growing area of research. The lecture is the first in a series of four, with the next on 26 October.
#quantumphysics #QuantumComputing #scienceandtechnology
#WomenInSTEM #GirlsInSTEM
#WednesdayWisdom



Australian Research Council
·

"The goal of our company, Silicon Quantum Computing, is to use the fundamental breakthroughs of our atomic revolution to build and operate the most precise and highest quality quantum computers. ... With more than two decades of Centre of Excellence funding from the Australian Research Council, our country's burgeoning quantum start-up sector has already attracted a sizeable workforce with the ingenuity and skills we need to make this happen.”
The ARC was proud to see Professor Michelle Simmons AO, Australian Laureate Fellow and Director of the ARC Centre for Quantum Computation & Communication Technology, deliver the first of four Boyer Lectures last night.



ABC.NET.AU
01 | The Atomic Revolution - ABC listen
Computing machinery that used to fill an entire room has now shrun

 Katalin Karikó and Drew Weissman – awarded the 2023 Nobel Prize in Physiology or Medicine – shared a passion for exploiting the use of mRNA in medical applications.

In our cells, genetic information encoded in DNA is transferred to messenger RNA (mRNA), which is used as a template for protein production. During the 1980s, efficient methods for producing mRNA without cell culture were introduced, called in vitro transcription. This decisive step accelerated the development of molecular biology applications in several fields. Ideas of using mRNA technologies for vaccine and therapeutic purposes also took off, but roadblocks lay ahead. Enthusiasm for developing the mRNA technology for clinical purposes was, therefore, initially limited.

These obstacles did not discourage the Hungarian biochemist Katalin Karikó, who was devoted to developing methods to use mRNA for therapy. During the early 1990s, when she was an assistant professor at the University of Pennsylvania, she remained true to her vision of realising mRNA as a therapeutic despite encountering difficulties in convincing research funders of the significance of her project. A new colleague of Karikó at her university was the immunologist Drew Weissman. He was interested in dendritic cells, which have important functions in immune surveillance and the activation of vaccine-induced immune responses. Spurred by new ideas, a fruitful collaboration between the two soon began, focusing on how different RNA types interact with the immune system.

Karikó and Weissman noticed that dendritic cells recognise in vitro transcribed mRNA as a foreign substance, which leads to their activation and the release of inflammatory signaling molecules. They wondered why the in vitro transcribed mRNA was recognised as foreign while mRNA from mammalian cells did not give rise to the same reaction.

The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

Learn more

Press release: https://bit.ly/3RypmGw 

Advanced information: https://bit.ly/3rrshGw